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AASS Antibody

Product Specifications

Background

This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.

NCBI Gene ID

10157

Swiss Prot

Q9UDR5

Accession Number

Q9UDR5

Host

Rabbit

Reactivity

Human

Immunogen

This AASS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 805-834 amino acids from the C-terminal region of human AASS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-621

Calculated Molecular Weight

102 kDa

Fragment

Rabbit Ig

Symbol

AASS

NCBI Official Name

Alpha-aminoadipic semialdehyde synthase, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Sacksteder, K.A., et al. Am. J. Hum. Genet. 66 (6) :1736-1743 (2000)

Background Reference 02

Papes, F., et al. Biochem. J. 344 PT 2, 555-563 (1999) :

Other Product Names

Alpha-aminoadipic semialdehyde synthase, mitochondrial, LKR/SDH, Lysine ketoglutarate reductase, LKR, LOR, Saccharopine dehydrogenase, SDH, AASS

Tested Applications

WB, Flow

Protein ID

46396032

Physical Properties

Liquid

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