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USF1 Antibody

Product Specifications

Background

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL) . Two transcript variants encoding distinct isoforms have been identified for this gene.

NCBI Gene ID

7391

Swiss Prot

P22415

Accession Number

P22415

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This USF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-201 amino acids from the Central region of human USF1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Symbol

USF1

NCBI Official Name

Upstream stimulatory factor 1

NCBI Organism

Homo sapiens

Background Reference 01

Jablonski, K.A., et al. Diabetes 59 (10) :2672-2681 (2010)

Background Reference 02

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 03

Bussiere, F.I., et al. Cell. Microbiol. 12 (8) :1124-1133 (2010)

Background Reference 04

Naukkarinen, J., et al. Circ Cardiovasc Genet 2 (5) :522-529 (2009)

Other Product Names

Upstream stimulatory factor 1, Class B basic helix-loop-helix protein 11, bHLHb11, Major late transcription factor 1, USF1, BHLHB11, USF

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

137170

Physical Properties

Liquid

Curated Selection

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