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ICAM2 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.

NCBI Gene ID

3384

Swiss Prot

P13598

Accession Number

P13598

Host

Rabbit

Reactivity

Human

Immunogen

This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-586

Calculated Molecular Weight

31 kDa

Fragment

Rabbit Ig

Symbol

ICAM2

NCBI Official Name

Intercellular adhesion molecule 2

NCBI Organism

Homo sapiens

Background Reference 01

Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)

Background Reference 02

Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)

Background Reference 03

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 04

Sato, H., et al. Biochim. Biophys. Acta 1790 (10) :1198-1205 (2009)

Other Product Names

Intercellular adhesion molecule 2, ICAM-2, CD102, ICAM2

Tested Applications

WB, Flow

Protein ID

115502404

Physical Properties

Liquid

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