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PPRC1 Antibody

Product Specifications

Background

The protein encoded by this gene is similar to PPAR-gamma coactivator 1 (PPARGC1/PGC-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (NRF1) . This protein has been shown to interact with NRF1. It is thought to be a functional relative of PPARGC1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals.

NCBI Gene ID

23082

Swiss Prot

Q5VV67

Accession Number

Q5VV67

Host

Rabbit

Reactivity

Human

Immunogen

This PPRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1636-1664 amino acids from the C-terminal region of human PPRC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

178 kDa

Fragment

Rabbit Ig

Symbol

PPRC1

NCBI Official Name

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Reiling, E., et al. Eur. J. Hum. Genet. 17 (8) :1056-1062 (2009)

Background Reference 02

Vercauteren, K., et al. J. Biol. Chem. 284 (4) :2307-2319 (2009)

Background Reference 03

Raharijaona, M., et al. PLoS ONE (11), E7964 (2009) :

Background Reference 04

Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)

Other Product Names

Peroxisome proliferator-activated receptor gamma coactivator-related protein 1, PGC-1-related coactivator, PRC, PPRC1, KIAA0595

Tested Applications

WB, IHC-P

Protein ID

74756889

Physical Properties

Liquid

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