ASAP3 Antibody

Product Specifications

Background

This gene encodes a member of a subfamily of ADP-ribosylation factor (Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

55616

Swiss Prot

Q8TDY4

Accession Number

Q8TDY4

Host

Rabbit

Reactivity

Human, Hamster

Immunogen

This ASAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human ASAP3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

99 kDa

Fragment

Rabbit Ig

Symbol

ASAP3

NCBI Official Name

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3

NCBI Organism

Homo sapiens

Background Reference 01

Ismail, S.A., et al. Cell 141 (5) :812-821 (2010)

Background Reference 02

Ha, V.L., et al. J. Biol. Chem. 283 (22) :14915-14926 (2008)

Background Reference 03

Fang, Z., et al. Mol. Cell Proteomics 5 (8) :1437-1449 (2006)

Background Reference 04

Okabe, H., et al. Int. J. Oncol. 24 (1) :43-48 (2004)

Other Product Names

Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1, ASAP3, DDEFL1, UPLC1