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UPP2 Antibody

Product Specifications

Background

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2 (') -deoxyuridine as substrates.

NCBI Gene ID

151531

Swiss Prot

O95045

Accession Number

O95045

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This UPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

36 kDa

Fragment

Rabbit Ig

Symbol

UPP2

NCBI Official Name

Uridine phosphorylase 2

NCBI Organism

Homo sapiens

Background Reference 01

Maestrini, E., et al. Mol. Psychiatry 15 (9) :954-968 (2010)

Background Reference 02

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Background Reference 03

Johansson, M. Biochem. Biophys. Res. Commun. 307 (1) :41-46 (2003)

Background Reference 04

Russell, R.L., et al. J. Biol. Chem. 276 (16) :13302-13307 (2001)

Other Product Names

Uridine phosphorylase 2, UPase 2, UrdPase 2, UPP2

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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