ASCL2 Antibody

Product Specifications

Background

This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.

NCBI Gene ID

430

Swiss Prot

Q99929

Accession Number

Q99929

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ASCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human ASCL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat, Xenopus, Bovine, Zebrafish

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

20 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

ASCL2

NCBI Official Name

Achaete-scute homolog 2

NCBI Organism

Homo sapiens

Background Reference 01

Stange, D.E., et al. Gut 59 (9) :1236-1244 (2010)

Background Reference 02

Eeles, R.A., et al. Nat. Genet. 41 (10) :1116-1121 (2009)

Background Reference 03

Barrett, J.C., et al. Nat. Genet. 41 (6) :703-707 (2009)

Background Reference 04

Shahib, M.N., et al.Reprod Med 51 (11) :892-896 (2006)

Other Product Names

Achaete-scute homolog 2, ASH-2, hASH2, Class A basic helix-loop-helix protein 45, bHLHa45, Mash2, ASCL2, BHLHA45, HASH2

Tested Applications

Protein ID

12644476

Physical Properties

Liquid

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