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FOSL2 Antibody

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

NCBI Gene ID

2355

Swiss Prot

P15408

Accession Number

P15408

Host

Rabbit

Reactivity

Human, Hamster

Immunogen

This FOSL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from the Central region of human FOSL2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

FOSL2

NCBI Official Name

Fos-related antigen 2

NCBI Organism

Homo sapiens

Background Reference 01

Bozec, A., et al. J. Cell Biol. 190 (6) :1093-1106 (2010)

Background Reference 02

Bolat, I., et al. Folia Histochem. Cytobiol. 48 (2) :197-201 (2010)

Background Reference 03

Reich, N., et al. Arthritis Rheum. 62 (1) :280-290 (2010)

Background Reference 04

Maurer, B., et al. Circulation 120 (23) :2367-2376 (2009)

Other Product Names

Fos-related antigen 2, FRA-2, FOSL2, FRA2

Tested Applications

WB, IHC-P

Protein ID

120487

Physical Properties

Liquid

Frequently Asked Questions

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