TNFAIP8 Antibody
Product Specifications
Background
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
NCBI Gene ID
25816
Swiss Prot
O95379
Accession Number
O95379
Host
Rabbit
Reactivity
Human
Immunogen
This TNFAIP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human TNFAIP8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Symbol
TNFAIP8
NCBI Official Name
Tumor necrosis factor alpha-induced protein 8
NCBI Organism
Homo sapiens
Background Reference 01
Dong, Q.Z., et al. Cancer Sci. 101 (6) :1562-1569 (2010)
Background Reference 02
Zhang, L.J., et al. J. Biol. Chem. 284 (10) :6156-6168 (2009)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Other Product Names
Tumor necrosis factor alpha-induced protein 8, TNF alpha-induced protein 8, Head and neck tumor and metastasis-related protein, MDC-313, NF-kappa-B-inducible DED-containing protein, NDED, SCC-S2, TNF-induced protein GG2-1, TNFAIP8
Tested Applications
WB, Flow
Physical Properties
Liquid
Frequently Asked Questions
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