BCL11B Antibody

Product Specifications

Background

This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.

NCBI Gene ID

64919

Swiss Prot

Q9C0K0

Accession Number

Q9C0K0

Host

Rabbit

Reactivity

Human

Immunogen

This BCL11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-334 amino acids from the Central region of human BCL11B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

96 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:16000

Symbol

BCL11B

NCBI Official Name

B-cell lymphoma/leukemia 11B

NCBI Organism

Homo sapiens

Background Reference 01

Ganguli-Indra, G., et al. Exp. Dermatol. 18 (11) :994-996 (2009)

Background Reference 02

Cherrier, T., et al. Oncogene 28 (38) :3380-3389 (2009)

Background Reference 03

Ganguli-Indra, G., et al. PLoS ONE (4), E5367 (2009) :

Background Reference 04

Cismasiu, V.B., et al. Virology 380 (2) :173-181 (2008)

Other Product Names

B-cell lymphoma/leukemia 11B, BCL-11B, B-cell CLL/lymphoma 11B, COUP-TF-interacting protein 2, Radiation-induced tumor suppressor gene 1 protein, hRit1, BCL11B, CTIP2, RIT1