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RPL27A Antibody

Product Specifications

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes derived from this gene are dispersed through the genome.

NCBI Gene ID

6157

Swiss Prot

P46776

Accession Number

P46776

Host

Rabbit

Reactivity

Human, Hamster

Immunogen

This RPL27A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-138 amino acids from the C-terminal region of human RPL27A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

17 kDa

Fragment

Rabbit Ig

Symbol

RPL27A

NCBI Official Name

60S ribosomal protein L27a

NCBI Organism

Homo sapiens

Background Reference 01

Kapp, L.D., et al. Annu. Rev. Biochem. 73, 657-704 (2004) :

Background Reference 02

Mazumder, B., et al. Cell 115 (2) :187-198 (2003)

Background Reference 03

Andersen, J.S., et al. Curr. Biol. 12 (1) :1-11 (2002)

Background Reference 04

Bortoluzzi, S., et al. Bioinformatics 17 (12) :1152-1157 (2001)

Other Product Names

60S ribosomal protein L27a, RPL27A

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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