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CTBP1 Antibody

Product Specifications

Background

This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

NCBI Gene ID

1487

Swiss Prot

Q13363

Accession Number

Q13363

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-438 amino acids from the C-terminal region of human CTBP1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

48 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

CTBP1

NCBI Official Name

C-terminal-binding protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Roukens, M.G., et al. Nat. Cell Biol. 12 (10) :933-942 (2010)

Background Reference 02

Choi, H.J., et al. Biochem. Biophys. Res. Commun. 400 (3) :396-402 (2010)

Background Reference 03

Merrill, J.C., et al. J. Mol. Biol. 398 (5) :657-671 (2010)

Background Reference 04

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Other Product Names

C-terminal-binding protein 1, CtBP1, 111-, CTBP1, CTBP

Tested Applications

WB

Protein ID

6014741

Physical Properties

Liquid

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