RORA Antibody

Product Specifications

Background

RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene.

NCBI Gene ID

6095

Swiss Prot

P35398

Accession Number

P35398

Host

Rabbit

Reactivity

Human

Immunogen

This RORA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-222 amino acids from human RORA.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Symbol

RORA

NCBI Official Name

Nuclear receptor ROR-alpha

NCBI Organism

Homo sapiens

Background Reference 01

Lechtken, A., Biochem. Biophys. Res. Commun. 358 (3), 890-896 (2007)

Background Reference 02

Lanoix, D., Hum. Reprod. 21 (8), 1981-1989 (2006)

Background Reference 03

Boukhtouche, F., J. Neurochem. 96 (6), 1778-1789 (2006)

Background Reference 04

Klar, J., Eur. J. Hum. Genet. 13 (8), 928-934 (2005)

Other Product Names

Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, Nuclear receptor subfamily 1 group F member 1, RAR-related orphan receptor A, Retinoid-related orphan receptor-alpha, RORA, NR1F1, RZRA