IMMP1L Antibody

Product Specifications

Background

The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]) .

NCBI Gene ID

196294

Swiss Prot

Q96LU5

Accession Number

Q96LU5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This IMMP1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-127 amino acids from the C-terminal region of human IMMP1L.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

19 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

IMMP1L

NCBI Official Name

Mitochondrial inner membrane protease subunit 1

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care (2010) In press :

Background Reference 02

Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

Background Reference 03

Taylor, T.D., et al. Nature 440 (7083) :497-500 (2006)

Background Reference 04

Burri, L., et al. Mol. Biol. Cell 16 (6) :2926-2933 (2005)

Other Product Names

Mitochondrial inner membrane protease subunit 1, 3421-, IMP1-like protein, IMMP1L

Tested Applications

Protein ID

74752020

Physical Properties

Liquid

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