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P5F1B Antibody

Product Specifications

Background

This intronless gene was thought to be a transcribed pseudogene of POU class 5 homeobox 1, however, it has been reported that this gene can encode a functional protein. The encoded protein is nearly the same length as and highly similar to the POU class 5 homeobox 1 transcription factor, has been shown to be a weak transcriptional activator and may play a role in carcinogenesis and eye development.

NCBI Gene ID

5462

Swiss Prot

Q06416

Accession Number

Q06416

Host

Rabbit

Reactivity

Human

Immunogen

This P5F1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-242 amino acids from the C-terminal region of human P5F1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

39 kDa

Fragment

Rabbit Ig

Symbol

POU5F1B

NCBI Official Name

Putative POU domain, class 5, transcription factor 1B

NCBI Organism

Homo sapiens

Background Reference 01

Kastler, S., et al. Prostate 70 (6) :666-674 (2010)

Background Reference 02

White, K.L., et al. Twin Res Hum Genet 13 (1) :43-56 (2010)

Background Reference 03

Crowther-Swanepoel, D., et al. Nat. Genet. 42 (2) :132-136 (2010)

Background Reference 04

Gudmundsson, J., et al. Nat. Genet. 41 (10) :1122-1126 (2009)

Other Product Names

Putative POU domain, class 5, transcription factor 1B, Oct4-pg1, Octamer-binding protein 3-like, Octamer-binding transcription factor 3-like, POU5F1B

Tested Applications

WB, Flow

Protein ID

357528826

Physical Properties

Liquid

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