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SP8 Antibody

Product Specifications

Background

Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity) .

NCBI Gene ID

221833

Swiss Prot

Q8IXZ3

Accession Number

Q8IXZ3

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SP8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

49 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SP8

NCBI Official Name

Transcription factor Sp8

NCBI Organism

Homo sapiens

Background Reference 01

Lee, M.T., et al. Mol. Psychiatry (2010) In press :

Background Reference 02

Jugessur, A., et al. PLoS ONE (7), E11493 (2010) :

Background Reference 03

Barber, M.J., et al. PLoS ONE (3), E9763 (2010) :

Background Reference 04

Eeles, R.A., et al. Nat. Genet. 41 (10) :1116-1121 (2009)

Other Product Names

Transcription factor Sp8, Specificity protein 8, SP8

Tested Applications

WB

Protein ID

300669678

Physical Properties

Liquid

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