GCN5 Antibody

Product Specifications

Background

GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. This protein has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles.

NCBI Gene ID

2648

Swiss Prot

Q92830

Accession Number

Q92830

Host

Rabbit

Reactivity

Human

Immunogen

This GCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human GCN5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

94 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

KAT2A

NCBI Official Name

Histone acetyltransferase KAT2A

NCBI Organism

Homo sapiens

Background Reference 01

Sabo, A., Mol. Cell. Biol. 28 (7), 2201-2212 (2008)

Background Reference 02

Wiper-Bergeron, N., Proc. Natl. Acad. Sci. U.S.A. 104 (8), 2703-2708 (2007)

Background Reference 03

Oishi, H., J. Biol. Chem. 281 (1), 20-26 (2006)

Background Reference 04

Kikuchi, H., Gene 347 (1), 83-97 (2005)

Other Product Names

Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5