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OAZ2 Antibody

Product Specifications

Background

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq].

NCBI Gene ID

4947

Swiss Prot

O95190

Accession Number

O95190

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This OAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-151 amino acids from the C-terminal region of human OAZ2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-401

Calculated Molecular Weight

21 kDa

Fragment

Rabbit Ig

Symbol

OAZ2

NCBI Official Name

Ornithine decarboxylase antizyme 2

NCBI Organism

Homo sapiens

Background Reference 01

Geerts, D., et al. Int. J. Cancer 126 (9) :2012-2024 (2010)

Background Reference 02

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

Background Reference 03

Mangold, U., et al. Biochem. J. 385 (PT 1), 21-28 (2005) :

Background Reference 04

Chen, H., et al. J. Biol. Chem. 277 (48) :45957-45961 (2002)

Other Product Names

Ornithine decarboxylase antizyme 2, AZ2, ODC-Az 2, OAZ2

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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