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SPRR2A Antibody

Product Specifications

Background

Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.

NCBI Gene ID

6700

Swiss Prot

P35326

Accession Number

P35326

Host

Rabbit

Reactivity

Human

Immunogen

This SPRR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-72 amino acids from the C-terminal region of human SPRR2A.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

8 kDa

Fragment

Rabbit IgG

Applications Notes

For WB starting dilution is: 1:1000

Symbol

SPRR2A

NCBI Official Name

Small proline-rich protein 2A

NCBI Organism

Homo sapiens

Background Reference 01

Kainu, K., et al. Exp. Dermatol. 18 (2) :109-115 (2009)

Background Reference 02

Demetris, A.J., et al. J. Hepatol. 48 (2) :276-288 (2008)

Background Reference 03

Tong, L., et al. Invest. Ophthalmol. Vis. Sci. 47 (5) :1938-1946 (2006)

Background Reference 04

Hong, S.H., et al. Mol. Cells 17 (3) :477-484 (2004)

Other Product Names

Small proline-rich protein 2A, SPR-2A, 2-1, SPRR2A

Tested Applications

WB

Physical Properties

Liquid

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