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PDHA2 Antibody

Product Specifications

Background

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO (2) . It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) .

NCBI Gene ID

5161

Swiss Prot

P29803

Accession Number

P29803

Host

Rabbit

Reactivity

Human

Immunogen

This PDHA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 287-314 amino acids from the Central region of human PDHA2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

43 kDa

Fragment

Rabbit Ig

Symbol

PDHA2

NCBI Official Name

Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial

NCBI Organism

Homo sapiens

Background Reference 01

Pinheiro, A., et al. Mol. Genet. Metab. 99 (4) :425-430 (2010)

Background Reference 02

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 03

Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

Background Reference 04

Caruso, M., et al. J. Biol. Chem. 276 (48) :45088-45097 (2001)

Other Product Names

Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial, PDHE1-A type II, PDHA2, PDHAL

Tested Applications

WB, IHC-P

Physical Properties

Liquid

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