RPH3AL Antibody

Product Specifications

Background

The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

NCBI Gene ID

9501

Swiss Prot

Q9UNE2

Accession Number

Q9UNE2

Host

Rabbit

Reactivity

Human

Immunogen

This RPH3AL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the C-terminal region of human RPH3AL.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

34 kDa

Fragment

Rabbit Ig

Symbol

RPH3AL

NCBI Official Name

Rab effector Noc2

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J. Phd, et al. Mol. Med. (2010) In pressShanmugam, C., et al. Biotech Histochem 84 (2) :39-45 (2009) Katkoori, V.R., et al. Front. Biosci. 13, 1050-1061 (2008) Matsumoto, M., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (22) :8313-8318 (2004) Manabe, S., et al. Biochem. Biophys. Res. Commun. 316 (1) :218-225 (2004)