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PRSS1 Antibody

Product Specifications

Background

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

NCBI Gene ID

5644

Swiss Prot

P07477

Accession Number

P07477

Host

Rabbit

Reactivity

Human

Immunogen

This PRSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human PRSS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

27 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

PRSS1

NCBI Official Name

Trypsin-1

NCBI Organism

Homo sapiens

Background Reference 01

Joergensen, M.T., et al. Am. J. Gastroenterol. 105 (8) :1876-1883 (2010)

Background Reference 02

Gasiorowska, A., et al. Dig. Dis. Sci. (2010) In press :

Background Reference 03

Szmola, R., et al. J. Med. Genet. 47 (5) :348-350 (2010)

Background Reference 04

Nakanuma, S., et al. Int. J. Oncol. 36 (4) :793-800 (2010)

Other Product Names

Trypsin-1, Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, Alpha-trypsin chain 1, Alpha-trypsin chain 2, PRSS1, TRP1, TRY1, TRYP1

Tested Applications

WB

Protein ID

136408

Physical Properties

Liquid

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