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HIST1H2BJ Antibody

Product Specifications

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq].

NCBI Gene ID

8970

Swiss Prot

P06899

Accession Number

P06899

Host

Rabbit

Reactivity

Human

Immunogen

This HIST1H2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the Central region of human HIST1H2BJ.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Xenopus, Rat, Mouse, Bovine, Monkey, Chicken, Zebrafish

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-372

Calculated Molecular Weight

14 kDa

Fragment

Rabbit Ig

Symbol

HIST1H2BJ

NCBI Official Name

Histone H2B type 1-J

NCBI Organism

Homo sapiens

Background Reference 01

Shi, J., et al. Nature 460 (7256) :753-757 (2009)

Background Reference 02

Benyamin, B., et al. Am. J. Hum. Genet. 84 (1) :60-65 (2009)

Background Reference 03

Kim, S.C., et al. Mol. Cell 23 (4) :607-618 (2006)

Background Reference 04

Beck, H.C., et al. Mol. Cell Proteomics 5 (7) :1314-1325 (2006)

Other Product Names

Histone H2B type 1-J, Histone H2B1, Histone H2Br, H2B/r, HIST1H2BJ, H2BFR

Tested Applications

WB, IHC-P, Flow

Protein ID

7404367

Physical Properties

Liquid

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