ETS1 Antibody
Product Specifications
Background
ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (summary by Dwyer et al., 2007 [PubMed 17986575]) .
NCBI Gene ID
2113
Swiss Prot
P14921
Accession Number
P14921
Host
Rabbit
Reactivity
Human
Immunogen
This ETS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human ETS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit IgG
Symbol
ETS1
NCBI Official Name
Protein C-ets-1
NCBI Organism
Homo sapiens
Background Reference 01
Harris, T.A., et al. Arterioscler. Thromb. Vasc. Biol. 30 (10) :1990-1997 (2010) He, C.F., et al. Lupus 19 (10) :1181-1186 (2010) Russell, L., et al. Cytokine 51 (3) :217-226 (2010) Li, T., et al. Pharm Biol 48 (2) :161-165 (2010) Kunderfranco, P., et al. PLoS ONE (5), E10547 (2010) :
Other Product Names
Protein C-ets-1, p54, ETS1, EWSR2
Tested Applications
WB, IF, Flow
Protein ID
119641
Physical Properties
Liquid
Frequently Asked Questions
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