ETS1 Antibody

Product Specifications

Background

ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (summary by Dwyer et al., 2007 [PubMed 17986575]) .

NCBI Gene ID

2113

Swiss Prot

P14921

Accession Number

P14921

Host

Rabbit

Reactivity

Human

Immunogen

This ETS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human ETS1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

50 kDa

Fragment

Rabbit IgG

Symbol

ETS1

NCBI Official Name

Protein C-ets-1

NCBI Organism

Homo sapiens

Background Reference 01

Harris, T.A., et al. Arterioscler. Thromb. Vasc. Biol. 30 (10) :1990-1997 (2010) He, C.F., et al. Lupus 19 (10) :1181-1186 (2010) Russell, L., et al. Cytokine 51 (3) :217-226 (2010) Li, T., et al. Pharm Biol 48 (2) :161-165 (2010) Kunderfranco, P., et al. PLoS ONE (5), E10547 (2010) :