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MCHR1 Antibody

Product Specifications

Background

The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.

NCBI Gene ID

2847

Swiss Prot

Q99705

Accession Number

Q99705

Host

Rabbit

Reactivity

Human

Immunogen

This MCHR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-422 amino acids from the C-terminal region of human MCHR1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-342

Calculated Molecular Weight

46 kDa

Fragment

Rabbit Ig

Symbol

MCHR1

NCBI Official Name

Melanin-concentrating hormone receptor 1

NCBI Organism

Homo sapiens

Background Reference 01

Miyamoto-Matsubara, M., et al. Ann. N. Y. Acad. Sci. 1200, 112-119 (2010) :

Background Reference 02

Yerges, L.M., et al. J. Bone Miner. Res. 24 (12) :2039-2049 (2009)

Background Reference 03

Miller, C.L., et al. Schizophr. Res. 113 (2-3), 259-267 (2009) :

Background Reference 04

Gavalas, N.G., et al. Exp. Dermatol. 18 (5) :454-463 (2009)

Other Product Names

Melanin-concentrating hormone receptor 1, MCH receptor 1, MCH-R1, MCHR-1, G-protein coupled receptor 24, MCH-1R, MCH1R, MCHR, SLC-1, Somatostatin receptor-like protein, MCHR1, GPR24, SLC1

Tested Applications

WB, IHC-P, Flow

Protein ID

33860175

Physical Properties

Liquid

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