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APCS Antibody

Product Specifications

Background

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

NCBI Gene ID

325

Swiss Prot

P02743

Accession Number

P02743

Host

Rabbit

Reactivity

Human

Immunogen

This APCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-331

Calculated Molecular Weight

25 kDa

Fragment

Rabbit Ig

Symbol

APCS

NCBI Official Name

Serum amyloid P-component

NCBI Organism

Homo sapiens

Background Reference 01

Song, Z., et al. Atherosclerosis 211 (1) :90-95 (2010)

Background Reference 02

Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

Background Reference 03

McGeachie, M., et al. Circulation 120 (24) :2448-2454 (2009)

Background Reference 04

Lu, J., et al. Nature 456 (7224) :989-992 (2008)

Other Product Names

Serum amyloid P-component, SAP, 95S alpha-1-glycoprotein, Serum amyloid P-component (1-203), APCS, PTX2

Tested Applications

WB, IHC-P

Protein ID

730704

Physical Properties

Liquid

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