PPP1R3A Antibody
Product Specifications
Background
The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase. [provided by RefSeq].
NCBI Gene ID
5506
Swiss Prot
Q16821
Accession Number
Q16821
Host
Rabbit
Reactivity
Human
Immunogen
This PPP1R3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 754-782 amino acids from the Central region of human PPP1R3A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
126 kDa
Fragment
Rabbit Ig
Symbol
PPP1R3A
NCBI Official Name
Protein phosphatase 1 regulatory subunit 3A
NCBI Organism
Homo sapiens
Background Reference 01
Yoshida, T., et al. Int. J. Mol. Med. 24 (2) :233-246 (2009)
Background Reference 02
Yoshida, T., et al. Genomics 93 (3) :221-226 (2009)
Background Reference 03
Gieger, C., et al. PLoS Genet. (11), E1000282 (2008) :
Background Reference 04
Savage, D.B., et al. PLoS Med. (1), E27 (2008) :
Other Product Names
Protein phosphatase 1 regulatory subunit 3A, Protein phosphatase 1 glycogen-associated regulatory subunit, Protein phosphatase type-1 glycogen targeting subunit, RG1, PPP1R3A, PP1G
Tested Applications
WB, Flow
Protein ID
298286906
Physical Properties
Liquid
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog