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CB2 Antibody

Product Specifications

Background

The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein) -coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

NCBI Gene ID

1269

Swiss Prot

P34972

Accession Number

P34972

Host

Rabbit

Reactivity

Human

Immunogen

This CB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-356 amino acids from the C-terminal region of human CB2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Growth Factors

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-328

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Symbol

CNR2

NCBI Official Name

Cannabinoid receptor 2

NCBI Organism

Homo sapiens

Background Reference 01

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 02

Larrinaga, G., et al. Histol. Histopathol. 25 (9) :1133-1138 (2010)

Background Reference 03

Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :

Background Reference 04

Taylor, A.H., et al. Histochem. Cell Biol. 133 (5) :557-565 (2010)

Other Product Names

Cannabinoid receptor 2, CB-2, CB2, hCB2, CX5, CNR2, CB2A, CB2B

Tested Applications

WB, IHC-P, Flow

Protein ID

461697

Physical Properties

Liquid

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