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SCARF2 Antibody

Product Specifications

Background

The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL) . This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

NCBI Gene ID

91179

Swiss Prot

Q96GP6

Accession Number

Q96GP6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This SCARF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-854 amino acids from the C-terminal region of human SCARF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

92 kDa

Fragment

Rabbit Ig

Symbol

SCARF2

NCBI Official Name

Scavenger receptor class F member 2

NCBI Organism

Homo sapiens

Background Reference 01

Anastasio, N., et al. Am. J. Hum. Genet. 87 (4) :553-559 (2010)

Background Reference 02

Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

Background Reference 03

Ishii, J., et al. J. Biol. Chem. 277 (42) :39696-39702 (2002)

Other Product Names

Scavenger receptor class F member 2, SRECRP-1, Scavenger receptor expressed by endothelial cells 2 protein, SREC-II, SCARF2, SREC2, SREPCR

Tested Applications

WB, Flow

Protein ID

380865486

Physical Properties

Liquid

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