ZNF197 Antibody
Product Specifications
Background
ZNF197 product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. ZNF197 is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described.
NCBI Gene ID
10168
Swiss Prot
O14709
Accession Number
O14709
Host
Rabbit
Reactivity
Human
Immunogen
This ZNF197 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the N-terminal region of human ZNF197.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-247
Calculated Molecular Weight
119 kDa
Fragment
Rabbit Ig
Symbol
ZNF197
NCBI Official Name
Zinc finger protein 197
NCBI Organism
Homo sapiens
Background Reference 01
Li, Z., et al. EMBO J. 22 (8) :1857-1867 (2003)
Background Reference 02
Gonsky, R., et al. Nucleic Acids Res. 25 (19) :3823-3831 (1997)
Background Reference 03
Calabro, V., et al. Hum. Genet. 95 (1) :18-21 (1995)
Background Reference 04
Pengue, G., et al. Hum. Mol. Genet. 2 (6) :791-796 (1993)
Other Product Names
Zinc finger protein 197, Zinc finger protein with KRAB and SCAN domains 9, ZnF20, pVHL-associated KRAB domain-containing protein, ZNF197, ZKSCAN9, ZNF166
Tested Applications
WB, IHC-P
Physical Properties
Liquid
Curated Selection
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