ZNF197 Antibody

Product Specifications

Background

ZNF197 product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. ZNF197 is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described.

NCBI Gene ID

10168

Swiss Prot

O14709

Accession Number

O14709

Host

Rabbit

Reactivity

Human

Immunogen

This ZNF197 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the N-terminal region of human ZNF197.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

119 kDa

Fragment

Rabbit Ig

Symbol

ZNF197

NCBI Official Name

Zinc finger protein 197

NCBI Organism

Homo sapiens

Background Reference 01

Li, Z., et al. EMBO J. 22 (8) :1857-1867 (2003)

Background Reference 02

Gonsky, R., et al. Nucleic Acids Res. 25 (19) :3823-3831 (1997)

Background Reference 03

Calabro, V., et al. Hum. Genet. 95 (1) :18-21 (1995)

Background Reference 04

Pengue, G., et al. Hum. Mol. Genet. 2 (6) :791-796 (1993)

Other Product Names

Zinc finger protein 197, Zinc finger protein with KRAB and SCAN domains 9, ZnF20, pVHL-associated KRAB domain-containing protein, ZNF197, ZKSCAN9, ZNF166