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5HT3E Antibody

Product Specifications

Background

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.

NCBI Gene ID

285242

Swiss Prot

A5X5Y0

Accession Number

A5X5Y0

Host

Rabbit

Reactivity

Human

Immunogen

This 5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human 5HT3E.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-244

Calculated Molecular Weight

51 kDa

Fragment

Rabbit Ig

Symbol

HTR3E

NCBI Official Name

5-hydroxytryptamine receptor 3E

NCBI Organism

Homo sapiens

Background Reference 01

Walstab, J., et al. J. Biol. Chem. 285 (35) :26956-26965 (2010)

Background Reference 02

Hammer, C., et al. Pharmacogenomics 11 (7) :943-950 (2010)

Background Reference 03

Lennertz, L., et al. Eur Neuropsychopharmacol 20 (6) :414-420 (2010)

Background Reference 04

Goecke, T.W., et al. Acta Obstet Gynecol Scand 89 (1) :7-14 (2010)

Other Product Names

5-hydroxytryptamine receptor 3E, 5-HT3-E, 5-HT3E, Serotonin receptor 3E, HTR3E

Tested Applications

WB, Flow

Physical Properties

Liquid

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