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MCAF2 Antibody

Product Specifications

Background

Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable) .

NCBI Gene ID

80063

Swiss Prot

Q5U623

Accession Number

Q5U623

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human MCAF2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-228

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Symbol

ATF7IP2

NCBI Official Name

Activating transcription factor 7-interacting protein 2

NCBI Organism

Homo sapiens

Background Reference 01

Adkins, D.E., et al. Mol. Psychiatry (2010) In press :

Background Reference 02

Ichimura, T., et al. J. Biol. Chem. 280 (14) :13928-13935 (2005)

Other Product Names

Activating transcription factor 7-interacting protein 2, ATF7-interacting protein 2, MBD1-containing chromatin-associated factor 2, ATF7IP2, MCAF2

Tested Applications

WB, IHC-P, Flow

Protein ID

143352739

Physical Properties

Liquid

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