PAX7 Antibody
Product Specifications
Background
PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5081
Swiss Prot
P23759
Accession Number
P23759
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PAX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the C-terminal region of human PAX7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
PAX7
NCBI Official Name
Paired box protein Pax-7
NCBI Organism
Homo sapiens
Background Reference 01
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 02
Williamson, D., et al. J. Clin. Oncol. 28 (13) :2151-2158 (2010)
Background Reference 03
Xynos, A., et al. Stem Cells 28 (5) :965-973 (2010)
Background Reference 04
Edwards, T.L., et al. Ann. Hum. Genet. 74 (2) :97-109 (2010)
Other Product Names
Paired box protein Pax-7, HuP1, PAX7, HUP1
Tested Applications
WB, IHC-P
Protein ID
8247951
Physical Properties
Liquid
Frequently Asked Questions
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