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COL5A1 Antibody

Product Specifications

Background

COL5A1 encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. COL5A1 product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq].

NCBI Gene ID

1289

Swiss Prot

P20908

Accession Number

P20908

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This COL5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human COL5A1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

184 kDa

Fragment

Rabbit Ig

Symbol

COL5A1

NCBI Official Name

Collagen alpha-1 (V) chain

NCBI Organism

Homo sapiens

Background Reference 01

Vitart, V., et al. Hum. Mol. Genet. 19 (21) :4304-4311 (2010)

Background Reference 02

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :

Background Reference 03

Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

Background Reference 04

Posthumus, M., et al. Med Sci Sports Exerc (2010) In press :

Other Product Names

Collagen alpha-1 (V) chain, COL5A1

Tested Applications

WB, IHC-P

Protein ID

85687376

Physical Properties

Liquid

Frequently Asked Questions

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