COL5A1 Antibody
Product Specifications
Background
COL5A1 encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. COL5A1 product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. [provided by RefSeq].
NCBI Gene ID
1289
Swiss Prot
P20908
Accession Number
P20908
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This COL5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the N-terminal region of human COL5A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-212
Calculated Molecular Weight
184 kDa
Fragment
Rabbit Ig
Symbol
COL5A1
NCBI Official Name
Collagen alpha-1 (V) chain
NCBI Organism
Homo sapiens
Background Reference 01
Vitart, V., et al. Hum. Mol. Genet. 19 (21) :4304-4311 (2010)
Background Reference 02
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Background Reference 03
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 04
Posthumus, M., et al. Med Sci Sports Exerc (2010) In press :
Other Product Names
Collagen alpha-1 (V) chain, COL5A1
Tested Applications
WB, IHC-P
Protein ID
85687376
Physical Properties
Liquid
Curated Selection
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