CMKOR1 Antibody
Product Specifications
Background
CXCR7 encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV) . Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq].
NCBI Gene ID
57007
Swiss Prot
P25106
Accession Number
P25106
Host
Rabbit
Reactivity
Human
Immunogen
This CMKOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-362 amino acids from the C-terminal region of human CMKOR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
ACKR3
NCBI Official Name
Atypical chemokine receptor 3
NCBI Organism
Homo sapiens
Background Reference 01
Berahovich, R.D., et al. J. Immunol. 185 (9) :5130-5139 (2010)
Background Reference 02
Watanabe, K., et al. Arthritis Rheum. 62 (11) :3211-3220 (2010)
Background Reference 03
Hattermann, K., et al. Cancer Res. 70 (8) :3299-3308 (2010)
Background Reference 04
Miekus, K., et al. Folia Histochem. Cytobiol. 48 (1) :104-111 (2010)
Other Product Names
Atypical chemokine receptor 3, C-X-C chemokine receptor type 7, CXC-R7, CXCR-7, Chemokine orphan receptor 1, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, RDC-1, ACKR3, CMKOR1, CXCR7, GPR159, RDC1
Tested Applications
WB, Flow
Protein ID
115502380
Physical Properties
Liquid
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