CYP2A7 Antibody

Product Specifications

Background

CYP2A7 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. CYP2A7, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

NCBI Gene ID

1549

Swiss Prot

P20853

Accession Number

P20853

Host

Rabbit

Reactivity

Human

Immunogen

This CYP2A7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-148 amino acids from the Central region of human CYP2A7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat, Mouse, Rabbit

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

CYP2A7

NCBI Official Name

Cytochrome P450 2A7

NCBI Organism

Homo sapiens

Background Reference 01

Fukami, T., et al. Pharmacogenomics J. 6 (6) :401-412 (2006) Nelson, D.R., et al. Pharmacogenetics 14 (1) :1-18 (2004) Oscarson, M., et al. Hum. Mutat. 20 (4) :275-283 (2002) Godoy, W., et al. Carcinogenesis 23 (4) :611-616 (2002) Koskela, S., et al. Biochem. Pharmacol. 57 (12) :1407-1413 (1999)