LILRA2 Antibody
Product Specifications
Background
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811) . LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.
NCBI Gene ID
11027
Swiss Prot
Q8N149
Accession Number
Q8N149
Host
Rabbit
Reactivity
Human
Immunogen
This LILRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-81 amino acids from the Central region of human LILRA2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=55-193
Calculated Molecular Weight
53 kDa
Fragment
Rabbit Ig
Symbol
LILRA2
NCBI Official Name
Leukocyte immunoglobulin-like receptor subfamily A member 2
NCBI Organism
Homo sapiens
Background Reference 01
Mosbruger, T.L., et al. J. Infect. Dis. 201 (9) :1371-1380 (2010)
Background Reference 02
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 03
Jones, D.C., et al. Eur. J. Immunol. 39 (11) :3195-3206 (2009)
Background Reference 04
Chen, Y., et al. J. Mol. Biol. 386 (3) :841-853 (2009)
Other Product Names
Leukocyte immunoglobulin-like receptor subfamily A member 2, CD85 antigen-like family member H, Immunoglobulin-like transcript 1, ILT-1, Leukocyte immunoglobulin-like receptor 7, LIR-7, CD85h, LILRA2, ILT1, LIR7
Tested Applications
WB, Flow
Protein ID
37537906
Physical Properties
Liquid
Curated Selection
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