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ANGPT1 Antibody

Product Specifications

Background

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

NCBI Gene ID

284

Swiss Prot

Q15389

Accession Number

Q15389

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig, Bovine

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=55-185

Calculated Molecular Weight

58 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:2000

Symbol

ANGPT1

NCBI Official Name

Angiopoietin-1

NCBI Organism

Homo sapiens

Background Reference 01

Fang, X., et al. J. Biol. Chem. 285 (34) :26211-26222 (2010)

Background Reference 02

Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)

Background Reference 03

Choe, J.Y., et al. Joint Bone Spine 77 (4) :340-344 (2010)

Background Reference 04

Roberts, K.E., et al. Gastroenterology 139 (1) :130-139 (2010)

Other Product Names

Angiopoietin-1, ANG-1, ANGPT1, KIAA0003

Tested Applications

WB

Protein ID

12229574

Physical Properties

Liquid

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