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LHFPL5 Antibody

Product Specifications

Background

This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. Mutations in this gene result in deafness in humans, and a mutation in a similar gene in mice results in deafness and vestibular dysfunction with severe degeneration of the organ of Corti. It is proposed to function in hair bundle morphogenesis.

NCBI Gene ID

222662

Swiss Prot

Q8TAF8

Accession Number

Q8TAF8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This LHFPL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the C-terminal region of human LHFPL5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

24 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LHFPL5

NCBI Official Name

Tetraspan membrane protein of hair cell stereocilia

NCBI Organism

Homo sapiens

Background Reference 01

Cosetti, M., et al. Ann. Otol. Rhinol. Laryngol. 117 (11) :827-833 (2008)

Background Reference 02

Shabbir, M.I., et al. J. Med. Genet. 43 (8) :634-640 (2006)

Background Reference 03

Longo-Guess, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 102 (22) :7894-7899 (2005)

Other Product Names

Tetraspan membrane protein of hair cell stereocilia, Lipoma HMGIC fusion partner-like 5 protein, LHFPL5, TMHS

Tested Applications

WB

Protein ID

74751349

Physical Properties

Liquid

Frequently Asked Questions

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