LCOR Antibody

Product Specifications

Background

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box (Fernandes et al., 2003 [PubMed 12535528]) .

NCBI Gene ID

84458

Swiss Prot

Q96JN0

Accession Number

Q96JN0

Host

Rabbit

Reactivity

Human

Immunogen

This LCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-350 amino acids from the C-terminal region of human LCOR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

LCOR

NCBI Official Name

Ligand-dependent corepressor

NCBI Organism

Homo sapiens

Background Reference 01

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

Background Reference 02

Palijan, A., et al. J. Biol. Chem. 284 (44) :30275-30287 (2009)

Background Reference 03

Palijan, A., et al. J. Biol. Chem. 284 (44) :30264-30274 (2009)

Background Reference 04

Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)

Other Product Names

Ligand-dependent corepressor, LCoR, Mblk1-related protein 2, LCOR, KIAA1795, MLR2

Tested Applications

Protein ID

108936028

Physical Properties

Liquid

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