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TGF-a Antibody [SPM357]

Product Specifications

Background

This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF-a is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

NCBI Gene ID

7039

Swiss Prot

P01135

Host

Mouse

Reactivity

Human, Bovine, Rat, Mouse

Immunogen

A 17-amino acid peptide from the C-terminus of the rat protein was used as the immunogen for this TGF a antibody.

Clonality

Monoclonal

Clone

SPM357

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies, Antibody Pairs

Field of Research

Growth Factors

Purification

Protein G affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG1, kappa

Symbol

TGFA

NCBI Official Name

Transforming growth factor, alpha

NCBI Organism

Homo sapiens

Other Product Names

TFGAProtransforming growth factor alpha, EGF-like TGF, TGF-alpha

Tested Applications

Flow, IF

Physical Properties

Liquid

Frequently Asked Questions

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