TGF-a Antibody [SPM357]
Product Specifications
Background
This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. TGF-a is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.
NCBI Gene ID
7039
Swiss Prot
P01135
Host
Mouse
Reactivity
Human, Bovine, Rat, Mouse
Immunogen
A 17-amino acid peptide from the C-terminus of the rat protein was used as the immunogen for this TGF a antibody.
Clonality
Monoclonal
Clone
SPM357
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies, Antibody Pairs
Field of Research
Growth Factors
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Fragment
IgG1, kappa
Symbol
TGFA
NCBI Official Name
Transforming growth factor, alpha
NCBI Organism
Homo sapiens
Other Product Names
TFGAProtransforming growth factor alpha, EGF-like TGF, TGF-alpha
Tested Applications
Flow, IF
Physical Properties
Liquid
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