What is the catalog number for Bax Antibody [SPM336]?

The catalog number for Bax Antibody [SPM336] is 34-157.

What sizes are available for Bax Antibody [SPM336]?

Bax Antibody [SPM336] is available in the following size(s): 100 µg.

Is Bax Antibody [SPM336] in stock?

Bax Antibody [SPM336] is currently made to order / not held in immediate stock. Contact us for lead time.

Bax Antibody [SPM336]

Product Specifications

Background

Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

NCBI Gene ID

581

Swiss Prot

Q07812

Host

Mouse

Reactivity

Human, Monkey

Immunogen

Amino acids 3-16 (GSGEQPRGGGPTSS) from the human protein were used as the immunogen for this anti-Bax antibody.

Clonality

Monoclonal

Clone

SPM336

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Autophagy, Cancer

Purification

Protein G affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG1

Specificity

Does not react with mouse and rat

Applications Notes

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes. 2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.