Prolactin Receptor Antibody [SPM213]
Product Specifications
Background
It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.
NCBI Gene ID
5618
Swiss Prot
P16471
Host
Mouse
Reactivity
Human
Immunogen
Semi-purified human prolactin receptor was used as the immunogen for this anti-Prolactin Receptor antibody.
Clonality
Monoclonal
Clone
SPM213
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Protein G affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=34-155
Fragment
IgG1, kappa
Applications Notes
1. Staining of formalin/paraffin tissues requires digestion of tissue sections with Pepsin at 1mg/ml Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37oC.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
PRLR
NCBI Official Name
Prolactin receptor
NCBI Organism
Homo sapiens
Other Product Names
PRLR, HPRL receptor, PRL-R, HPRLrI, Prolactin receptor
Tested Applications
Flow, IF, IHC
Physical Properties
Liquid
Curated Selection
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