Recombinant MART-1 / Melan-A Antibody [MLANA/1761R]

Product Specifications

Background

MART-1/Melan-A is a protein antigen that is found on the surface of melanocytes. Antibodies against the antigen are used in the medical specialty of anatomic pathology in order to recognize cells of melanocytic differentiation, useful for the diagnosis of a melanoma. The MART-1/Melan-A antigen is specific for the melanocyte lineage, found in normal skin, the retina, and melanocytes, but not in other normal tissues. It is thus useful as a marker for melanocytic tumors (melanomas) with the caveat that it is normally found in benign nevi as well. [Wiki]

NCBI Gene ID

2315

Swiss Prot

Q16655

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Human protein was used as the immunogen for this recombinant Melan-A antibody.

Clonality

Recombinant Monoclonal

Clone

MLANA/1761R

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

Protein A affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG, k

Applications Notes

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.