Recombinant Wilms Tumor 1 Antibody [WT1/1434R]
Product Specifications
Background
Wilms tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
NCBI Gene ID
7490
Swiss Prot
P19544
Host
Rabbit
Reactivity
Human, Rat
Immunogen
A recombinant protein was used as the immunogen for the recombinant WT1 antibody.
Clonality
Recombinant Monoclonal
Clone
WT1/1434R
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cell Cycle, Cancer, Apoptosis
Purification
Protein A affinity chromatography
Concentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=34-079
Fragment
IgG, k
Applications Notes
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Symbol
WT1
NCBI Official Name
Wilms tumor 1
NCBI Organism
Homo sapiens
Other Product Names
WT1, GUD, WAGR, WIT-2, WT33, AWT1, NPHS4, EWS-WT1
Tested Applications
IF, IHC-P, Flow
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
