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Recombinant PDCD1 / PD-1 Antibody [PDCD1/1410R]

Product Specifications

Background

PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

NCBI Gene ID

5133

Swiss Prot

Q15116

Host

Rabbit

Reactivity

Human

Immunogen

A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

Clonality

Recombinant Monoclonal

Clone

PDCD1/1410R

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Cancer, Cell Cycle

Purification

Protein A affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG, k

Applications Notes

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Symbol

PDCD1

NCBI Official Name

Programmed cell death 1

NCBI Organism

Mus musculus

Other Product Names

PD-1 Antibody: PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1, PD1, Programmed cell death protein 1, Protein PD-1, PDCD1, PDCD-1

Tested Applications

IHC-P, IF, Flow

Physical Properties

Liquid

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