Recombinant PDCD1 / PD-1 Antibody [PDCD1/1410R]

Product Specifications

Background

PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

NCBI Gene ID

5133

Swiss Prot

Q15116

Host

Rabbit

Reactivity

Human

Immunogen

A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

Clonality

Recombinant Monoclonal

Clone

PDCD1/1410R

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Cancer, Cell Cycle

Purification

Protein A affinity chromatography

Concentration

0.2 mg/mL

Buffer

PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

Fragment

IgG, k

Applications Notes

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.